Chinese Manufacturer Supply 527-72-0 with Cheapest Price, Buy High Grade 2-Thiophenecarboxylic acid
- Molecular Formula:C5H4O2S
- Molecular Weight:128.152
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:0.00639mmHg at 25°C
- Melting Point:125-127 °C(lit.)
- Refractive Index:1.5160 (estimate)
- Boiling Point:260 °C at 760 mmHg
- PKA:3.49(at 25℃)
- Flash Point:117.8 °C
- PSA：65.54000
- Density:1.401 g/cm3
- LogP:1.44630
2-Thiophenecarboxylic acid(Cas 527-72-0) Usage
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Uses
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Thiophene-2-carboxylic acid is a thiophenecarboxylic acid in which the carboxy group is located at position 2. It is a conjugate acid of a thiophene-2-carboxylate. |
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Chemical Properties
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white to light yellow crystal powder
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Synthesis Reference(s)
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The Journal of Organic Chemistry, 30, p. 3520, 1965 DOI: 10.1021/jo01021a055
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Consumer Uses
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ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
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InChI:InChI=1/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)/p-1
527-72-0 Relevant articles
LIQUID-PHASE CATALYTIC OXIDATION OF 2-METHOXYMETHYLTHIOPHENE
Leichenko, A. A.,Schedrinskaya, T. V.,Volkov, M. N.
, p. 714 - 718 (1980)
The oxidation of 2-methoxymethylthiophen...
CLEAVAGE DIRECTION OF C-O BOND IN ANION RADICALS OF METHYL ESTERS OF AROMATIC ACIDS IN APROTIC SOLVENTS
Gul'tai, V. P.,Rubinskaya, T. Ya.,Korotaeva, L. M.
, p. 1499 - 1500 (1982)
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Facile production of vitamin B3 and other heterocyclic carboxylic acids using an efficient Ag/ZnO/graphene-Si hybrid nanocatalyst
Attia, Yasser A.,Vázquez, Carlos Vázquez,Mohamed, Yasser M. A.
, p. 203 - 218 (2017)
Abstract: High yield of vitamin B3 is pr...
Palladium-promoted One-step Carboxylation of Aromatic Compounds with Carbon Monoxide
Fujiwara, Yuzo,Kawauchi, Tomio,Taniguchi, Hiroshi
, p. 220 - 221 (1980)
The one-step carboxylation of aromatic c...
Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence
Payne, Karl A. P.,Marshall, Stephen A.,Fisher, Karl,Rigby, Stephen E. J.,Cliff, Matthew J.,Spiess, Reynard,Cannas, Diego M.,Larrosa, Igor,Hay, Sam,Leys, David
, p. 2865 - 2878 (2021)
The UbiD family of reversible (de)carbox...
Gram-scale synthesis of carboxylic acids via catalytic acceptorless dehydrogenative coupling of alcohols and hydroxides at an ultralow Ru loading
Chen, Cheng,Cheng, Hua,Verpoort, Francis,Wang, Zhi-Qin,Wu, Zhe,Yuan, Ye,Zheng, Zhong-Hui
, (2021/12/13)
Acceptorless dehydrogenative coupling (A...
Transformation of Thioacids into Carboxylic Acids via a Visible-Light-Promoted Atomic Substitution Process
Fu, Qiang,Liang, Fu-Shun,Lou, Da-Wei,Pan, Gao-Feng,Wang, Rui,Wu, Min,Xie, Kai-Jun
supporting information, p. 2020 - 2024 (2022/03/31)
A visible-light-promoted atomic substitu...
Photoinduced FeCl3-Catalyzed Alkyl Aromatics Oxidation toward Degradation of Polystyrene at Room Temperature?
Zhang, Guoxiang,Zhang, Zongnan,Zeng, Rong
supporting information, p. 3225 - 3230 (2021/09/28)
While polystyrene is widely used in dail...
527-72-0 Process route
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- 527-72-0
2-thiophenylcarboxylic acid
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- 75021-56-6
[2-(4-methoxy-phenyl)-cyclopropyl]-thiophen-2-yl-methanone
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- 100-09-4
4-methoxybenzoic acid
Conditions
| Conditions |
Yield |
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C15H16O2S; With oxygen; sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 11h;
With hydrogenchloride; In water;
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90%
10%
10% |
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- 527-72-0
2-thiophenylcarboxylic acid
Conditions
| Conditions |
Yield |
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With trifluoroacetic acid; sodium nitrite; In chloroform; at 0 - 5 ℃; for 1h;
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54% |
527-72-0 Upstream products
527-72-0 Downstream products
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5380-42-7
thiophene-2-carboxylic acid methyl ester
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59303-19-4
propyl thiophene‐2‐carboxylate
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2810-04-0
Ethyl thiophene-2-carboxylate
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35250-80-7
thiophene-2-carboxylic acid isopentyl ester
English
![[2-(4-methoxy-phenyl)-cyclopropyl]-thiophen-2-yl-methanone](/upload/2024/4/34870a51-a5bb-45fd-bf13-076a454cf97a.png)
